Table 4.
Comparison of predictive ability of MSU microscopy, the dipstick test, and the UF-5000 test in patients without taking prior antibiotics in 2 weeks (n=269).
| Test | Variables | Sensitivity | Specificity | PPV | NPV | AUC (95%CI) | P-value | NRI,% (95%CI) | P-value |
|---|---|---|---|---|---|---|---|---|---|
| MSU | WBC | 26.7% | 97.3% | 75.0% | 81.3% | 0.620 (0.553-0.686) | – | – | – |
| Dipstick | NIT | 26.6% | 96.4% | 70.8% | 80.2% | 0.615 (0.559-0.671) | Ref a. | 0 | Ref a . |
| WBC | 67.2% | 81.2% | 53.8% | 88.4% | 0.742 (0.678-0.806) | Ref b. | 0 | Ref b . | |
| NIT and WBC | 21.9% | 98.5% | 82.4% | 79.5% | 0.602 (0.550-0.654) | Ref c. | 0 | Ref c . | |
| NIT or WBC | 71.9% | 78.6% | 52.3% | 89.5% | 0.752 (0.690-0.815) | Ref d. | 0 | Ref d . | |
| UF-5000 | BACT parameter e | 87.3% | 76.5% | 53.9% | 95.0% | 0.819 (0.768-0.870) | 7.32×10-7 | 37.4 (15.0-57.8) | 6.04×10-4 |
| WBC parameter f | 95.5% | 54.0% | 40.8% | 97.3% | 0.747 (0.705-0.790) | 0.81 | -1.9 (-17.5~13.7) | 1.00 | |
| BACT and WBC | 84.1% | 80.0% | 57.0% | 94.1% | 0.821 (0.767-0.874) | 1.32×10-10 | 39.9 (19.4-60.4) | 1.36×10-4 | |
| BACT or WBC | 98.5% | 51.0% | 40.0% | 99.0% | 0.748 (0.710-0.785) | 0.82 | -3.4 (19.0~12.2) | 0.66 |
PPV, positive predictive value; NPV, negative predictive value; AUC, area under the receiver operating curve; NRI, net reclassification index; CI, confidence interval; NIT, nitrite; BACT, bacteria count; WBC, white blood cells in urine; Ref., reference.
a
Compare NIT and BACT.
b
Compare dipstick WBC and UF-5000 WBC.
c
Compare NIT and WBC and BACT and WBC.
d
Compare NIT/WBC and BACT/BACT.
e
Parameter (+) was set as BACT ≥196 units/μl.
f
WBC parameter (+) was set as WBC≥14.7 cells/μl.