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. 2022 Sep 27;12:1021320. doi: 10.3389/fcimb.2022.1021320

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Copyright © 2022 Zhang, Gao, Zhu, Jin, Song, Dong, Li, Wang, Chen, Yang, Tan and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of diagnostic performance of Illumina and Nanopore for the main pathogens in BALF of patients with suspected CAP. (A), Confirmation/exclusion of pathogenic infection in 53 patients using Illumina, Nanopore and culture. *: The results were consistent with the clinical etiological diagnosis. (B), Contingency tables for the Illumina and Nanopore in detecting different classes of pathogenic microorganisms. Clinical etiological diagnosis was used as a reference method. (C). ROC curves stratified by classes of microbes.