Table 2. The SNP list for the two different instrumental variables (IV_CRP and IV_Asian).

	SNP	Chromosome	Positiona	EAb	ALT	EAF	Positional candidate gene	Estimate (SE)c,d	P-valued
IVCRP	rs3093077	1	159679636	C	A	0.146	CRP	0.389 (0.050)	4.25 × 10−15
	rs1205	1	159682233	C	T	0.328	CRP	0.213 (0.038)	1.97 × 10−8
	rs1130864	1	159683091	A	G	0.064	CRP	0.000 (0.075)	0.99
	rs1800947	1	159683438	C	G	0.979	CRP	0.205 (0.124)	0.10
IVAsian	rs3093068	1	159681364	C	G	0.142	CRP	0.391 (0.050)	5.51 × 10−15
	rs7553007	1	159698549	G	A	0.491	CRP	0.213 (0.038)	1.97 × 10−8
	rs7310409	12	121424861	G	A	0.525	HNF1A	0.128 (0.035)	3.01 × 10−4

ALT, alternative allele; BP, base pair; EA, effect allele; EAF, effect allele frequency; IV, instrumental variables; SE, standard error; SNP, single nucleotide polymorphism.

^aThe column of Position is presented base pairs based on Genome Reference Consortium Human Build 37 (GRCh37).

^bThe column of EA shows CRP increasing alleles.

^cThe estimates indicate a change of ln(eGFR) with an 1-unit increase in ln(hs-CRP).

^dP-values was estimated by linear regression (R, ‘glm’) with adjustment for sex, age, and study sites.