Table 1.

Demographic, clinical and biochemical characteristics among ALD patients, Alcoholic and non-alcoholic Controls.

Sl. No.	Parameters	a. ALD Patients (n = 128)	b. ALC Controls (n = 184)	c. NALC Control (n = 152)	P-value* a vs. b	P-value*a vs. c
1	Gender, Male%	100	100	100	–	–
2	Age (years)	45.2 ± 10.0	44.1 ± 8.8	43.9 ± 11	0.305	0.306
3	BMI (kg/m2)	20.59 ± 3.04	23.72 ± 3.75	25.48 ± 3.24	<0.001	<0.001
4	LSM (kPa)	N.A.	7.36 ± 3.53	6.26 ± 2.17	N.A.	N.A.
5	Total Bilirubin (mg/dl)	4.41 ± 5.33	1.11 ± 0.26	0.57 ± 0.03	<0.0001	<0.0001
6	Total Protein (g/dl)	6.83 ± 0.86	7.46 ± 0.52	7.32 ± 0.65	<0.0001	<0.0001
7	Albumin (g/dl)	3.28 ± 0.95	4.34 ± 0.38	4.36 ± 0.45	<0.0001	<0.0001
8	AST (IU/L)	99.12 ± 119.34	24.95 ± 5.29	25.95 ± 5.55	<0.0001	<0.0001
9	ALT (IU/L)	60.45 ± 83.43	32.70 ± 7.83	32.59 ± 10.33	<0.0001	<0.0001
10	ALP (IU/L)	300.86 ± 203.63	124.06 ± 22.42	141.03 ± 64.94	<0.0001	<0.0001
11	Haemoglobin (g/dl)	10.87 ± 2.69	14.1 ± 0.76	13.8 ± 1.24	<0.0001	<0.0001
Kolmogorov–Smirnov test to compare distribution of biochemical variables among the ALD patients, ALC, and NALC controls
		Kolmogorov–Smirnov Z, P-value**	Kolmogorov–Smirnov Z, P-value	Kolmogorov–Smirnov Z, P-value
	Total Bilirubin (mg/dl)	3.53, 0.0001	1.17, 0.124	0.93, 0.316
	Albumin (g/dl)	1.45, 0.030	0.51, 0.959	1.04, 0.226
	AST (IU/L)	2.96, 0.0001	0.71, 0.703	1.08, 0.194
	ALT (IU/L)	3.55, 0.0001	1.04, 0.231	0.92, 0.368
	ALKP (IU/L)	2.56, 0.0001	3.19, 0.0001	0.62, 0.972

**p-value obtained from Student’s t-test; Values are Mean ± SD.

**p-values obtained from Kolmogorov–Smirnov test for normality.

*p-value obtained from Student’s t-test; Values are Mean ± SD.

BMI, Body mass Index; LSM, Liver stiffness measurement; AST, Aspartate Transaminase; ALT, Alanine Transaminase; ALP, Alkaline Phosphatase.

Bold values are statistically significant.

NA, Not available.