Table 4.
Expression of CD14 and other pro- and anti-inflammatory cytokines in sera of individuals of the ALD, ALC, and NALC groups.
| Sl. No, | Parameters | a. ALD Patients(n = 128) | b. Alcoholic Controls (n = 184) |
c. Non-Alcoholic Control (n = 152) |
P-value* a vs. b | P-value*a vs. c |
|---|---|---|---|---|---|---|
| 1 | CD14 (ng/ml) | 267.98 ± 223.65 | 197.72 ± 115.11 | 152.11 ± 43.99 | 0.033 | <0.0001 |
| 2 | LBP (ng/ml) | 156.12 ± 128.47 | 131.68 ± 69.58 | 107.23 ± 45.91 | 0.198 | 0.006 |
| 3 | MD2 (ng/ml) | 1,212.35 ± 735.67 | 1,513.09 ± 1,108.69 | 2,055.79 ± 1,365.81 | 0.083 | <0.0001 |
| 4 | TLR-4 (ng/ml) | 4.01 ± 1.49 | 3.55 ± 2.07 | 2.89 ± 1.70 | 0.165 | <0.0001 |
| 5 | TNFα (pg/ml) | 199.70 ± 40.04 | 97.01 ± 15.16 | 20.21 ± 4.99 | <0.0001 | <0.0001 |
| 6 | IFNγ (pg/ml) | 4.81 ± 3.81 | 4.40 ± 1.93 | 3.20 ± 0.98 | 0.459 | 0.002 |
| 7 | IL-1β (pg/ml) | 237.03 ± 70.23 | 98.78 ± 12.64 | 57.67 ± 6.16 | <0.0001 | <0.0001 |
| 8 | IL-4 (pg/ml) | 0.95 ± 0.14 | 0.98 ± 0.12 | 1.17 ± 0.18 | 0.210 | <0.001 |
| 9 | IL-6 (pg/ml) | 3.89 ± 2.06 | 1.22 ± 0.83 | 0.71 ± 0.39 | <0.0001 | <0.0001 |
| 10 | IL-10 (pg/ml) | 8.77 ± 4.73 | 7.35 ± 3.93 | 9.82 ± 3.38 | 0.076 | 0.164 |
*p-value obtained from Student’s t-test. Bold values are statistically significant.