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Suggested sequences for second- and third-line treatment of clear-cell RCC.
Abbreviations: RCC, renal cell carcinoma; VEGFR, vascular endothelial growth factor receptor; TKI: tyrosine kinase inhibitor; ICI, immune checkpoint inhibitor; Sun: sunitinib; Paz: pazopanib; Cabo, cabozantinib; Nivo, nivolumab; Ipi: ipilimumab; Pembro, pembrolizumab; Axi, axitinib; Tivo, tivozanib; Lenva, Lenvatinib; Eve, everolimus.
