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. 2022 Oct 10;328(16):1604–1615. doi: 10.1001/jama.2022.18931

Table 3. Global Proportion of Individuals With at Least 1 of the 3 Long COVID Symptom Clusters.

Proportion with Long COVID symptom clusters among survivors, % (95% UI)a
3 mo after symptom onset 12 mo after symptom onset
All individuals 6.2 (2.4-13.3) 0.9 (0.3-2.0)b
Both sexes aged <20 yc 2.8 (0.9-7.0) 0.3 (0.1-0.8)
Women aged ≥20 y 10.6 (4.3-22.2) 1.7 (0.7-3.6)
Men aged ≥20 y 5.4 (2.2-11.7) 0.8 (0.3-1.8)
Hospitalized
Needed care in a general hospital ward 27.5 (12.1-47.8) 11.1 (4.7-19.7)
Females 34.8 (16.5-57.3) 15.1 (5.8-29.7)
Males 21.6 (8.9-40.3) 8.2 (2.9-17.7)
Needed care in an ICU 43.1 (22.6-65.2) 20.5 (9.8-32.9)
Females 51.9 (29.7-73.6) 26.6 (11.5-47.8)
Males 35.8 (17.1-58.1) 15.7 (6.0-31.9)
Not hospitalized
All individuals 5.7 (1.9-13.1) 0.7 (0.2-1.5)
Both sexes aged <20 yc 2.7 (0.8-6.7) 0.3 (0-0.8)
Women aged ≥20 y 9.9 (3.4-21.2) 1.3 (0.3-3.4)
Men aged ≥20 y 4.8 (1.5-11.3) 0.6 (0.1-1.5)

Abbreviations: ICU, intensive care unit; UI, uncertainty interval.

a

Long COVID was defined as having at least 1 of the 3 symptom clusters (persistent fatigue with bodily pain or mood swings; cognitive problems; or ongoing respiratory problems) 3 months after symptomatic SARS-CoV-2 infection. Additional details appear in eTables 14-16 in Supplement 1.

b

Among individuals with Long COVID symptoms 3 months after symptomatic SARS-CoV-2 infection, 15.1% (95% UI, 10.3%-21.2%) continued to experience symptoms at 12 months.

c

Data were insufficient to stratify proportion estimates by sex.