Table 1. Patient Characteristics.
| Variable | No. (%) | P value | |
|---|---|---|---|
| ASPECTS ≤3 (n = 106) | ASPECTS 4-5 (n = 96) | ||
| Age, mean (SD), y | 76.7 (9.6) | 75.6 (10.6) | .46 |
| Female | 54 (50.9) | 36 (37.5) | .055 |
| Male | 52 (49.1) | 60 (62.5) | |
| Modified Rankin Scale score before onset, median (IQR) | 0 (0-1) | 0 (0-1) | .38 |
| Baseline NIHSS score, median (IQR) | 23 (17-26) | 21 (18-25) | .14 |
| Medical history | |||
| Hypertension | 74 (69.8) | 67 (69.8) | >.99 |
| Diabetes | 24 (22.6) | 19 (19.8) | .62 |
| Hyperlipidemia | 30 (28.3) | 19 (19.8) | .16 |
| Atrial fibrillation | 64 (60.4) | 55 (57.3) | .66 |
| Current smoking | 18 (17.0) | 21 (21.9) | .38 |
| Blood pressure, mean (SD), mm Hga | |||
| Systolic | 159.5 (30.3) | 159.6 (27.3) | .99 |
| Diastolic | 86.4 (21.0) | 89.6 (18.2) | .25 |
| Laboratory tests | |||
| Cholesterol, mean (SD), mg/dLb | |||
| LDL | 110.8 (32.2) | 106.5 (32.7) | .39 |
| HDL | 56.7 (16.6) | 56.2 (16.9) | .86 |
| Blood glucose, median (IQR), mg/Lc | 138 (116-163) | 129 (116-147) | .16 |
| Creatinine, median (IQR), mg/dLd | 0.80 (0.66-1.08) | 0.83 (0.70-1.05) | .45 |
| CRP, median (IQR), mg/dLe | 0.25 (0.10-0.92) | 0.13 (0.06-0.37) | <.001 |
| Internal carotid artery occlusion | 55 (51.9) | 40 (41.7) | .15 |
| MRI | 95 (89.6) | 79 (82.3) | .13 |
| ASPECTS | NA | ||
| 0-2 | 8 (7.5) | 0 | |
| 3 | 98 (92.5) | 0 | |
| 4 | 0 | 56 (58.3) | |
| 5 | 0 | 40 (41.7) | |
| Infarction volume, median (IQR), mLf | 126 (83-168) | 89 (60-122) | <.001 |
| Intravenous rt-PA use | 28 (26.4) | 27 (28.1) | .79 |
| Time from onset to image, median (IQR), min | 198 (103-376) | 159 (101-400) | .46 |
| Time from onset to randomization, median (IQR), min | 224 (140-405) | 207 (145-427) | .62 |
| Time from onset to puncture, median (IQR), min | 263 (170-523) | 237 (165-388) | .38 |
| Time from onset to reperfusion, median (IQR), min | 320 (223-559) | 292 (207-479) | .33 |
| Reperfusion degree with TICI ≥2b | 47/56 (83.9) | 39/44 (88.6) | .50 |
| Stroke classification | |||
| Cardioembolic | 84 (79.2) | 75 (78.1) | .87 |
| Atherothrombotic | 5 (4.7) | 7 (7.3) | |
| Cryptogenic | 14 (13.2) | 11 (11.5) | |
| Other | 3 (2.8) | 3 (3.1) | |
Abbreviations: ASPECTS, Alberta Stroke Program Early Compute Tomography Score; CRP, C-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MRI, magnetic resonance imaging; NA, not applicable; NIHSS, National Institutes of Health Stroke Scale; rt-PA, recombinant tissue plasminogen activator; TICI, thrombolysis in the cerebral infarction.
Data missing for 2 participants for systolic and diastolic blood pressure.
To convert to mmol/L, multiply by 0.0259. Data missing for 33 participants for LDL cholesterol and 34 for HDL cholesterol.
To convert to mmol/L, multiply by 0.0555. Data missing for 2 participants for blood glucose.
To convert to μmol/L, multiply by 76.25.
To convert to mg/L, multiply by 10.
Data missing for 20 participants for infarction volume.