Table 2. Outcomes.
| Outcome | No. (%) | OR (95% CI) | P value | P value for interaction | |
|---|---|---|---|---|---|
| EVT group | No-EVT group | ||||
| ASPECTS ≤3 (n = 106), No. | 56 | 50 | NA | NA | NA |
| Primary outcome | |||||
| mRS score of 0-3 at 90 d | 12 (21.4) | 9 (18.0) | 1.24 (0.47-3.26) | .66 | .01 |
| Secondary outcomes | |||||
| mRS score of 0-2 at 90 d | 3 (5.4) | 6 (12.0) | 0.42 (0.10-1.77) | .23 | .003 |
| mRS score of 0-1 at 90 d | 0 | 2 (4.0) | NA | NA | NA |
| Ordinal shift across the range of mRS toward a better outcome | NA | NA | 1.56 (0.79-3.10) | .20 | .046 |
| Improvement of ≥8 NIHSS points at 48 h | 14 (25.0) | 4 (8.0) | 3.83 (1.17-12.6) | .03 | .60 |
| Safety outcomes | |||||
| Symptomatic intracranial hemorrhage within 48 h | 6 (10.7) | 3 (6.0) | 1.88 (0.44-7.95) | .39 | .98 |
| Any intracranial hemorrhage within 48 h | 37(66.1) | 16 (32.0) | 4.14 (1.84-9.32) | <.001 | .24 |
| Death within 90 d | 10 (17.9) | 14 (28.0) | 0.56 (0.22-1.40) | .22 | .47 |
| Recurrence of cerebral infarction within 90 d | 4 (7.1) | 1 (2.0) | 3.77 (0.41-34.9) | .24 | .054 |
| Decompressive craniectomy within 7 d | 7 (12.5) | 7 (14.0) | 0.88 (0.28-2.70) | .82 | .50 |
| ASPECTS 4-5 (n = 96), No. | 44 | 52 | NA | NA | NA |
| Primary outcome | |||||
| mRS score of 0-3 at 90 d | 19 (43.2) | 4 (7.7) | 9.12 (2.80-29.7) | <.001 | NA |
| Secondary outcomes | |||||
| mRS score of 0-2 at 90 d | 11 (25.0) | 2 (3.8) | 8.33 (1.73-40.0) | .008 | NA |
| mRS score of 0-1 at 90 d | 5 (11.4) | 1 (1.9) | 6.54 (0.73-58.3) | .09 | NA |
| Ordinal shift across the range of mRS toward a better outcome | NA | NA | 4.48 (2.07-9.71) | <.001 | NA |
| Improvement of 8 points or greater on the NIHSS at 48 h | 17 (38.6) | 5 (9.6) | 5.92 (1.96-17.8) | .002 | NA |
| Safety outcomes | |||||
| Symptomatic intracranial hemorrhage within 48 h | 3 (6.8) | 2 (3.8) | 1.83 (0.29-11.5) | .52 | NA |
| Any intracranial hemorrhage within 48 h | 21 (47.7) | 16 (30.8) | 2.05 (0.89-4.73) | .09 | NA |
| Death within 90 d | 8 (18.2) | 10 (19.2) | 0.93 (0.33-2.62) | .90 | NA |
| Recurrence of cerebral infarction within 90 d | 1 (2.3) | 6 (11.5) | 0.18 (0.02-1.54) | .12 | NA |
| Decompressive craniectomy within 7 d | 3 (6.8) | 7 (13.5) | 0.47 (0.11-1.94) | .30 | NA |
Abbreviations: ASPECTS, Alberta Stroke Program Early Computed Tomography Score; EVT, endovascular therapy; mRS, modified Rankin Scale; NA, not applicable; NIHSS, National Institutes of Health stroke scale; OR, odds ratio.