General patient information (four features) |
Gender, age, body weight (abbreviation: BW), height |
Substance abuse (three features) |
Smoking history, drinking history, history of other substance abuse |
Diagnosis and disorder history (three features) |
Diagnosis of schizophrenia, diagnosis of bipolar affective disorder, allergic history |
Blood types (two features) |
ABO blood type, Rh blood type |
Phenotypes, genotypes, and gene polymorphisms (13 features) |
MTHFR (C677T) polymorphism, MTHFR phenotype, HLA-B*1502 genotype, CYP2C19 genotype, CYP2C19 phenotype, CYP2D6 genotype, CYP2D6 phenotype, CYP2D6 (G4180C) polymorphism, CYP2D6 (G2988A) polymorphism, CYP2D6 (C2850T) polymorphism, CYP2D6 (G1846A) polymorphism, CYP2D6 (C100T) polymorphism, ApoE genotype |
Dosage regimens (three features) |
Daily dose of OLZ [abbreviation: daily dose (OLZ)], dosage regimen of OLZ, daily dose frequency of OLZ |
Combined drugs (280 features) |
Valproic acid, risperidone, rifampicin, warfarin, clozapine, sertraline, fluvoxamine, perphenazine, carbamazepine, fluoxetine, etc. |
Results of TDM measurements of other medications (24 features) |
Concentrations of valproic acid [abbreviation: C (Valproic acid)], sertraline, fluoxetine, fluvoxamine, risperidone, oxcarbazepine, venlafaxine, clozapine, lamotrigine, perphenazine, aripiprazole, etc. |
Information relating to biochemical analyses (140 features) |
Time of TDM blood sampling after first administration of OLZ (abbreviation: time of blood sampling after first administration), alanine transaminase (abbreviation: ALT), serum potassium (abbreviation: K), serum sodium (abbreviation: Na), absolute monocyte count (abbreviation: MONO#), white blood cell count (abbreviation: WBC), red blood cell count (abbreviation: RBC), serum creatinine (abbreviation: Cr), uric acid (abbreviation: UA), creatine kinase (abbreviation: CK), C-reactive protein (abbreviation: CRP), total cholesterol (abbreviation: TC), etc. |