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. 2022 Sep 26;24(39):7082–7087. doi: 10.1021/acs.orglett.2c02592

Table 1. ERED-Catalyzed Bioreduction of Chloroenone 1aa.

graphic file with name ol2c02592_0005.jpg

entry ERED c (%)b ee (%)c
1 103 89 88 (R)
2 110 99 94 (R)
3 112 7 n.d.
4 207 88 92 (R)
5 P1-A04 >99 78 (R)
6 P1-E01 72 77 (R)
7 P1-H09 78 85 (S)
a

For further details, see Table S1.

b

Determined by GC.

c

Determined by HPLC. Major enantiomer in parentheses. n.d.: not determined.