Table 1. ERED-Catalyzed Bioreduction of Chloroenone 1aa.
entry | ERED | c (%)b | ee (%)c |
---|---|---|---|
1 | 103 | 89 | 88 (R) |
2 | 110 | 99 | 94 (R) |
3 | 112 | 7 | n.d. |
4 | 207 | 88 | 92 (R) |
5 | P1-A04 | >99 | 78 (R) |
6 | P1-E01 | 72 | 77 (R) |
7 | P1-H09 | 78 | 85 (S) |
For further details, see Table S1.
Determined by GC.
Determined by HPLC. Major enantiomer in parentheses. n.d.: not determined.