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. 2022 Sep 26;13:882455. doi: 10.3389/fimmu.2022.882455

Figure 2.

Figure 2

Glucose and insulin homeostasis after 8 weeks of HFHS diets. (A) Glycemic excursion curves during OGTT (left, significant difference between LFLS vs. all the groups fed with HFHS diets) with the corresponding area under the curve analysis of glucose (right); (B) Insulinemic excursion curves during OGTT (left, significant difference between LFLS vs. all the groups fed with HFHS diets) and the corresponding area under the curve analysis; (C) HOMA-IR calculated using glucose and insulin AUCs (area under the curve) from OGTTs. *p < 0.05); **p < 0.01; ***p < 0.001); ****p < 0.00001). (D) Intestinal permeability as measure by sulfonic acid levels in blood after administration with the OGTT: #significant difference between LFLS versus HFHS group (p < 0.05). *significant difference between Hemp versus HFHS group (p < 0.05).