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. 2022 Sep 10;1(4):pgac187. doi: 10.1093/pnasnexus/pgac187

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© The Author(s) 2022. Published by Oxford University Press on behalf of National Academy of Sciences.

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Fig. 5. — Polygenomic infections exhibit reduced heterozygosity. (A to C) The individual R_H estimates for each of the clinical polygenomic samples collected from (A) Kédougou (red), (B) Thiès (orange), and (C) Richard Toll (blue). The open-faced square indicates the average R_H of the samples in each year and the dark line is the point estimate obtained for the entire region. The point estimate for the entire region and its associated 95% confidence interval are reported in the legend. The proportion of polygenomic infections inferred to be the result of cotransmission or superinfection with COI of two (COI = 2), three (COI = 3), or four strains (COI = 4) in Kédougou (D), Thiès (E), and Richard Toll (F), respectively . The error bars indicate two binomial SDs from the mean for each category.

Inline graphic — Polygenomic infections exhibit reduced heterozygosity. (A to C) The individual R_H estimates for each of the clinical polygenomic samples collected from (A) Kédougou (red), (B) Thiès (orange), and (C) Richard Toll (blue). The open-faced square indicates the average R_H of the samples in each year and the dark line is the point estimate obtained for the entire region. The point estimate for the entire region and its associated 95% confidence interval are reported in the legend. The proportion of polygenomic infections inferred to be the result of cotransmission or superinfection with COI of two (COI = 2), three (COI = 3), or four strains (COI = 4) in Kédougou (D), Thiès (E), and Richard Toll (F), respectively . The error bars indicate two binomial SDs from the mean for each category.