Table 2.
Uni- and multivariate prognostic analyses for DFS
| Variables | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| N | HR [95% CI] | p-value | N | HR [95% CI] | p-value | |
| Patient's age | 303 | 1.00 [0.99–1.01] | 0.839 | |||
| Gender, male vs. female | 303 | 1.04 [0.73–1.48] | 0.831 | |||
| Tumor site, head and neck vs. extremity | 382 | 0.00 [0.00- Inf] | 0.118 | |||
| Tumor site, internal trunk vs. extremity | 1.28 [0.90–1.81] | |||||
| Tumor site, superficial trunk vs. extremity | 0.68 [0.40–1.16] | |||||
| Tumor depth, superficial vs. deep | 128 | 0.26 [0.06–1.07] | 0.062 | |||
| Pathological type, leiomyosarcoma vs. UPS | 610 | 2.42 [1.65–3.54] | 2.06E−05 | 55 | 3.63 [0.28–46.61] | 0.322 |
| Pathological type, liposarcoma vs. UPS | 1.44 [1.00–2.06] | 55 | 1.97 [0.10–37.16] | 0.650 | ||
| Pathological type, myxofibrosarcoma vs. UPS | 1.01 [0.51–2.01] | 55 | 7.02 [0.33–150.7] | 0.213 | ||
| Pathological type, other vs. UPS | 0.78 [0.35–1.72] | 55 | 0 [0.00—Inf] | 0.999 | ||
| Pathological tumor size (cm) | 142 | 1.05 [1.02–1.09] | 1.39E−03 | 55 | 1.07 [0.98–1.17] | 0.155 |
| Pathological FNCLCC grade, 3 vs. 1–2 | 239 | 1.47 [0.93–2.33] | 0.098 | 55 | 6.84 [1.04–44.8] | 0.045 |
| Genetic profile, complex vs. simple | 598 | 1.17 [0.89–1.54] | 0.270 | |||
| CINSARC, high-risk vs. low-risk | 610 | 2.22 [1.70–2.90] | 4.35E−09 | 55 | 1.14 [0.26–4.93] | 0,865 |
| CSPG4, high vs. low | 610 | 1.49 [1.14–1.94] | 3.36E−03 | 55 | 10.47 [1.04–105.3] | 4.62E−02 |
The significant p-values are in bold
UPS Undifferentiated Pleomorphic Sarcoma, FNCLCC Fédération Nationale des Centres de Lutte Contre le Cancer