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Key targets of YGJ and YGJ-BBB.
| Group | KEGG pathway | Key targets |
|---|---|---|
| YGJ | PI3K-Akt signaling pathway | AKT1, CCND1, BCL2, EGFR, ERBB2, ERBB4, FGFR1, MTOR, GSK3B, GYS1, HSP90AA1, IGF1R, IL2, INSR, JAK2, KIT, MCL1, NOS3, NTRK1, PDGFRB, PIK3CA, PRKAA1, MAPK1, MAP2K1, RXRA, VEGFA |
| YGJ-BBB | Endocrine resistance | AKT1, CCND1, BCL2, BRAF, EGFR, ERBB2, ESR1, ESR2, MTOR, IGF1R, MMP2, MMP9, PIK3CA, MAPK1, MAP2K1 |
