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. 2022 Sep 23;12:1004652. doi: 10.3389/fonc.2022.1004652

Table 3A.

Subgroup analysis according to liver function (Child-pugh A vs Child-pugh B).

Child-pugh A (n = 116) Child-pugh B (n = 29) p value
mRECIST
Best response (n, %)
CR 9 (7.8) 0 (0) 0.205
PR 60 (51.7) 13 (44.8) 0.506
SD 38 (32.7) 10 (34.5) 0.860
PD 9 (7.8) 6 (20.7) 0.041
ORR (CR+PR) 69(59.5) 13 (44.8) 0.154
DCR (CR+PR+SD) 107 (92.2) 23 (79.3) 0.041
Conversion rate (n, %) 26 (22.4) 1 (3.4) 0.019

mRECIST, modified Response Evaluation Criteria in Solid Tumors; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; ORR, objective response rate; DCR, disease control rate.