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. 2022 Oct 10;5(10):e2235844. doi: 10.1001/jamanetworkopen.2022.35844

Table 2. Symptoms Reported Among Symptomatic People Testing Positive or Negative With a Rapid Antigen Test During the Omicron BA.1 Period,a Stratified by Age Group.

Symptoms Overall (n = 7283) No. (%) of participants P value (B-H corrected) Point estimate (95% CI)
Age ≥18 y (n = 5779) Age 12-17 y (n = 664) Age <12 y (n = 840)
Positive (n = 2419) Negative (n = 3360) Positive (n = 311) Negative (n = 353 Positive (n = 302) Negative (n = 538) Age ≥18 y vs 12-17 y among COVID-positive patients Age ≥18 y vs <12 y among COVID-positive patients Age ≥18 y vs 12-17 y among COVID-positive patients Age ≥18 y vs <12 y among COVID-positive patients
Fever 1534 (21.1) 733 (30.3) 492 (14.6) 84 (27.0) 52 (14.7) 104 (34.4) 69 (12.8) .23 (.46) .14 (.31) 1.12 (0.95-1.33) 0.88 (0.69-1.12)
Cough 4195 (57.6) 1626 (67.2) 1617 (48.1) 218 (70.1) 186 (52.7) 200 (66.2) 348 (64.7) .31 (.55) .73 (.90) 0.96 (0.88-1.04) 1.01 (0.91-1.13)
Shortness of breath 496 (6.8) 209 (8.6) 221 (6.6) 22 (7.1) 25 (7.1) 10 (3.3) 9 (1.7) .35 (.55) .001 (.002) 1.22 (0.66-2.28) 2.61 (1.26-5.42)
Fatigue 1316 (18.1) 538 (22.2) 664 (19.8) 33 (10.6) 33 (9.4) 23 (7.6) 25 (4.7) <.001 (.002) <.001 (.002) 2.10 (1.41-3.13) 2.92 (1.76-4.85)
Myalgia 1626 (22.3) 779 (32.2) 681 (20.3) 63 (20.3) 51 (14.5) 26 (8.6) 26 (4.8) <.001 (.002) <.001 (.002) 1.59 (1.1-2.31) 3.74 (2.44-5.74)
Headache 2347 (32.2) 898 (37.1) 1118 (33.3) 124 (39.9) 99 (28.1) 53 (17.6) 55 (10.2) .35 (.55) <.001 (.002) 0.93 (0.73-1.2) 2.12 (1.6-2.8)
Loss of taste or smell 288 (4.0) 141 (5.8) 112 (3.3) 18 (5.8) 12 (3.4) 1 (0.3) 4 (0.7) .98 (.98) <.001 (.002) 1.01 (0.14-7.17) 17.6 (2.36-131.05)
Sore throat 2899 (39.8) 1099 (45.4) 1364 (40.6) 140 (45.0) 121 (34.3) 77 (25.5) 98 (18.2) .89 (.93) <.001 (.002) 1.01 (0.83-1.23) 1.78 (1.42-2.24)
Congestion 2648 (36.4) 960 (39.7) 1156 (34.4) 126 (40.5) 111 (31.4) 91 (30.1) 204 (37.9) .78 (.90) .001 (.002) 0.98 (0.82-1.17) 1.32 (1.06-1.64)
Nausea 385 (5.3) 118 (4.9) 182 (5.4) 16 (5.1) 21 (6.0) 16 (5.3) 32 (6.0) .84 (.92) .75 (.90) 0.95 (0.57-1.58) 0.92 (0.47-1.81)
Diarrhea 370 (5.1) 119 (4.9) 71 (5.1) 12 (3.9) 38 (10.8) 13 (4.3) 17 (3.2) .41 (.60) .64 (.88) 1.27 (0.73-2.23) 1.14 (0.53-2.46)

Abbreviation: B-H, Benjamin-Hochberg.

a

December 1, 2021, to January 30, 2022.