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Effects of cell density and adaptation time on induction of acid adaptation by S. mutans BM71. Cells were adapted by incubation in pH 5.5 TYG medium at low (OD600 = 0.2) or high (OD600 = 0.6) density for various times before exposure to the killing pH of 3.5 for 3 h. Results represent the mean number of surviving cells ± SD from at least three independent cultures.
