Skip to main content
. Author manuscript; available in PMC: 2022 Oct 11.
Published in final edited form as: Eur J Nucl Med Mol Imaging. 2022 May 12;49(11):3705–3716. doi: 10.1007/s00259-022-05814-9

Figure 3.

Figure 3.

Detection of activated fibroblasts with [68Ga]Ga-FAPI-46 PET/CT in a murine model of bleomycin-induced lung fibrosis. PET/CT and VOI quantification of [68Ga]Ga-FAPI-46 uptake in bleomycin and control mice found significantly higher [68Ga]Ga-FAPI-46 uptake in the lungs of injured mice at (a, c) 30 min and (b, d) 60 min post-injection (n = 3–5). Lungs highlighted by yellow arrows. P values were calculated using Student’s two-tailed t-test (*P<0.05, **P<0.01, ***P<0.001).