Table 2.
Changes and between-group comparisons in the adapted Fuster-BEWAT score for all TANSNIP-PESA participants and the low and high SA subgroups
| Intervention | Control | Intervention effect | ||||
|---|---|---|---|---|---|---|
| N | mean (SD) | N | mean (SD) | Estimate (95% CI) | P-value | |
| Adapted Fuster-BEWAT score (all participants) (0–24) | ||||||
| Baseline | 425 | 16.2 (3.7) | 445 | 16.5 (3.5) | – | – |
| Year 1 | 425 | 17.1 (3.6) | 445 | 16.5 (3.5) | 0.83 (0.52–1.15)a | <0.001 |
| Year 3 | 408 | 16.6 (3.7) | 395 | 16.5 (3.6) | 0.24 (−0.10 to 0.59)a | 0.161 |
| Overall time trend | 468 | – | 474 | – | 0.49 (0.23–0.75)b | <0.001 |
| Adapted Fuster-BEWAT score (low SA participants) (0–24) | ||||||
| Baseline | 307 | 16.5 (3.7) | 320 | 16.7 (3.4) | – | – |
| Year 1 | 307 | 17.4 (3.6) | 320 | 16.7 (3.4) | 1.01 (0.63–1.39)a | <0.001 |
| Year 3 | 289 | 17.0 (3.5) | 272 | 16.7 (3.5) | 0.34 (−0.07 to 0.76)a | 0.105 |
| Overall time trend | 333 | – | 337 | – | 0.61 (0.30–0.93)b | <0.001 |
| Adapted Fuster-BEWAT score (high SA participants) (0–24) | ||||||
| Baseline | 118 | 15.4 (3.7) | 125 | 16.0 (3.6) | – | – |
| Year 1 | 118 | 16.2 (3.6) | 125 | 16.2 (3.6) | 0.38 (−0.20 to 0.95)a | 0.195 |
| Year 3 | 119 | 15.7 (3.8) | 123 | 16.0 (4.0) | 0.03 (−0.57 to 0.63)a | 0.927 |
| Overall time trend | 135 | – | 137 | – | 0.19 (−0.26 to 0.64)b | 0.405 |
Fuster-BEWAT score and estimate mean difference are expressed in points.
For the outcome analysis at Years 1 and 3, estimates were calculated using linear mixed effect regression models.
For the overall time trend, estimates were calculated with repeated measures regression models.
BEWAT, Blood pressure, Exercise (objectively measured PA and sedentary time), Weight (BMI), Alimentation (fruit and vegetable consumption), and Tobacco; PESA, Progression of Early Subclinical Atherosclerosis; SA, subclinical atherosclerosis; TANSNIP, Trans-Atlantic Network to study Stepwise Non-invasive Imaging as a tool for CVD Prognosis and prevention.