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Effect of angiotensin (Ang) II type 1 receptor blockade with valsartan, angiotensin-converting enzyme inhibition with captopril, angiotensinogen (AGT) siRNA, or their combination during 4 weeks on the levels of Ang I, Ang II, Ang III, and Ang-(1-7) in blood and kidney of spontaneously hypertensive rats. Modified from Uijl et al. (2019). *P < 0.05 vs. vehicle. LLOQ, lower limit of quantification.
