Bar-graph depicts the BP-lowering effects of different therapies shown as maximal reductions in nocturnal supine systolic BP from baseline (ΔSBP) after a single dose (PO) of the different medications given at 8 PM, or local heat (38°C) applied from 10 PM to 6 AM. *P<0.05 vs. placebo. Values are expressed as mean±SEM.
The table depicts the qualitative effect of these interventions on nocturnal diuresis (8 PM to 8 AM), and morning orthostatic tolerance (i.e., ability to endure orthostatic BP drop or hypotension) determined during a 10-minute standing test at 8 AM.