Table 6.
Comparison of differences in biochemical and hematological parameters in the standard dose (5 mg kg-1) DFO treatment group for 6 months.
| Characteristics | Alp ≤ 60(n = 13) Before |
After |
p Value | Alp > 60(n = 30) Before |
After | p Value |
|---|---|---|---|---|---|---|
| Aluminum (μg.L-1) | 32.7 ± 3.7 | 35.4 ± 14.0 | 0.594 | 58.2 ± 44.0 | 39.0 ± 19.2 | 0.061 |
| △aluminum* (μg.L-1) after DFO | 90.4 ± 40.0 | 66.1 ± 33.0 | 0.038 | 83.6 ± 27.3 | 51.1 ± 35.0 | 0.001 |
| Calcium (mg.dL-1) | 9.4 ± 0.8 | 9.4 ± 1.0 | 0.848 | 9.3 ± 1.1 | 9.2 ± 1.1 | 0.672 |
| Phosphate (mg.dL-1) | 6.6 ± 1.4 | 6.2 ± 1.4 | 0.506 | 5.8 ± 1.9 | 5.5 ± 1.7 | 0.222 |
| Intact parathyroid hormone (pg.mL-1) | 434.5 ± 447.2 | 431.4 ± 405.1 | 0.422 | 620.2 ± 604.6 | 751.5 ± 657.4 | 0.125 |
| Hematocrit (%) | 30.8 ± 4.4 | 31.8 ± 4.8 | 0.484 | 30.4 ± 6.6 | 31.2 ± 6.3 | 0.364 |
| Mean corpuscular volume*, fL | 90.8 ± 5.4 | 92.8 ± 5.9 | 0.077 | 88.1 ± 6.6 | 89.8 ± 7.2 | 0.004 |
| Erythropoietin dose changes* (unit)/month | 25179.5 ± 8505.6 | 22538.5 ± 38778.7 | 0.028 | 23691.4 ± 11607.1 | 22135.8 ± 11468.4 | 0.269 |
| Ferritin | 513.4 ± 260.7 | 474.1 ± 265.4 | 0.485 | 585.4 ± 397.0 | 587.5 ± 371.1 | 0.973 |
ALP: Alkaline Phosphatase.
*<0.05; **<0.01.