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. 2022 Oct 10;15:5785–5799. doi: 10.2147/JIR.S382573

Table 4.

Univariate and Multivariable Cox Regression Analyses of Clinical Parameters

Variables Univariate P Multivariate P
HR (95% CI) HR (95% CI)
Male (n, %) 0.753 (0.481, 0.108) 0.216
Age>70 (n, %) 1.616 (0.875, 2.742) 0.069 1.908 (1.054, 3.455) 0.033
Hypertension (n, %) 1.230 (0.733, 2.065) 0.433
Diabetes mellitus (n, %) 1.039 (0.328, 3.286) 0.948
CAD (n, %) 1.592 (0.392, 6.470) 0.516
COPD (n, %) 4.339 (1.371, 13.734) 0.013 2.511 (0.748, 8.423) 0.136
ESRD (n, %) 2.119 (0.777, 5.779) 0.142
Cerebral ischemia (n, %) 0.918 (0.424, 1.986) 0.827
Limb ischaemia (n, %) 2.177 (1.333, 3.556) 0.002 1.882 (1.141, 3.102) 0.013
Bowel ischaemia (n, %) 6.748 (2.942, 15.479) <0.001 1.500 (0.683, 3.291) 0.312
CRRT (n, %) 2.773 (1.719, 4.345) <0.001 1.919 (1.169, 3.151) 0.010
Coronary artery involvement (n, %) 1.815 (1.135, 2.901) 0.013 1.127 (0.649, 1.954) 0.672
SII≥3324.5 (n, %) 3.042 (1.970, 4.700) <0.001 2.467 (1.573, 3.868) <0.001
CABG (n, %) 2.663 (1.504, 4.717) <0.001 1.127 (1.149, 1.954) 0.050
CPB time (min) 1.001 (0.999, 1.003) 0.046 1.059 (0.615, 1.824) 0.595
Crossclamp time(min) 1.004 (1.000, 1.007) 0.033 1.001 (0.997, 1.005) 0.683

Abbreviations: CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; ESRD, end-stage renal disease; SII, systemic immune-inflammation index; CABG, coronary artery bypass graft; CRRT, continuous renal replacement therapy; CPB, cardiopulmonary bypass.