Table 3.
Univariate Analysis of Risk Factors for Enucleation Following OGI
Variable | Level | Odds Ratio | 95% CI Lower | 95% CI Upper | p-value | Type III p-value |
---|---|---|---|---|---|---|
Injury mechanism | Penetrating vs Rupture | 0.44 | 0.24 | 0.81 | 0.0082 | 0.0007 |
Perforating vs Rupture | 0.37 | 0.20 | 0.70 | 0.0019 | ||
Previous ocular surgery | Yes vs no | 1.64 | 1.06 | 2.56 | 0.0282 | |
Time to presentation (hours) | >24h vs <24h | 0.43 | 0.20 | 0.92 | 0.0306 | |
RAPD | Yes vs no | 6.44 | 3.37 | 12.28 | <0.0001 | |
IOFB | Yes vs no | 0.55 | 0.28 | 1.07 | 0.0787 | |
Zone of injury | 2 vs 1 | 1.49 | 0.78 | 2.84 | 0.2263 | <0.0001 |
3 vs 1 | 6.66 | 4.01 | 11.06 | <0.0001 | ||
Wound length | 5–10mm vs <5mm | 3.79 | 1.02 | 14.07 | 0.0468 | <0.0001 |
11–15mm vs <5mm | 16.44 | 4.80 | 56.27 | <0.0001 | ||
16–20mm vs <5mm | 21.64 | 5.97 | 78.40 | <0.0002 | ||
>20mm vs <5mm | 41.31 | 12.35 | 138.14 | <0.0003 | ||
Lens status pre-OGI | Pseudophakic vs phakic | 1.87 | 1.15 | 3.04 | 0.0117 | 0.0386 |
Aphakic vs phakic | 0.77 | 0.09 | 6.46 | 0.8080 | ||
Lens disruption including implant disruption | Yes vs no | 0.91 | 0.60 | 1.38 | 0.6718 | |
Uveal prolapse | Yes vs no | 6.10 | 3.11 | 11.99 | <0.0001 | |
Vitreous hemorrhage at time of wound closure | Yes vs no | 1.36 | 0.89 | 2.07 | 0.1548 | |
Intraocular inflammation with or without hypopyon at time of presentation | Yes vs no | 0.30 | 0.12 | 0.77 | 0.0123 | |
Retinal detachment | Yes vs no | 1.76 | 1.13 | 2.75 | 0.0126 | |
Endophthalmitis | Yes vs no | 1.28 | 0.50 | 3.29 | 0.6034 | |
Time to surgery from injury | >24h vs <24h | 0.77 | 0.44 | 1.35 | 0.3598 | |
Vitrectomy at time of globe repair | Weck-Cel vs no | 1.04 | 0.61 | 1.79 | 0.8824 | 0.8413 |
Anterior vitrectomy vs no | <0.001 | <0.001 | >999.999 | 0.9837 | ||
Posterior vitrectomy vs no | 0.57 | 0.17 | 1.96 | 0.3754 | ||
Lensectomy | Yes vs no | 1.03 | 0.50 | 2.12 | 0.9434 | |
Age (Years) | Continuous | 1.01 | 1.00 | 1.02 | 0.0144 | |
Presenting VA LogMAR | Continuous | 13.35 | 6.59 | 27.07 | <0.0001 | |
Presenting VA | <20/400 vs ≥20/400 | 16.48 | 3.99 | 68.13 | 0.0001 |
Notes: Bolded rows within the table denote statistically significant risk factors and their associated odds ratios and p-values.
Abbreviations: RAPD, relative afferent pupillary defect; IOFB, intraocular foreign body.