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. 2022 Oct 10;16:3339–3350. doi: 10.2147/OPTH.S377137

Table 3.

Univariate Analysis of Risk Factors for Enucleation Following OGI

Variable Level Odds Ratio 95% CI Lower 95% CI Upper p-value Type III p-value
Injury mechanism Penetrating vs Rupture 0.44 0.24 0.81 0.0082 0.0007
Perforating vs Rupture 0.37 0.20 0.70 0.0019
Previous ocular surgery Yes vs no 1.64 1.06 2.56 0.0282
Time to presentation (hours) >24h vs <24h 0.43 0.20 0.92 0.0306
RAPD Yes vs no 6.44 3.37 12.28 <0.0001
IOFB Yes vs no 0.55 0.28 1.07 0.0787
Zone of injury 2 vs 1 1.49 0.78 2.84 0.2263 <0.0001
3 vs 1 6.66 4.01 11.06 <0.0001
Wound length 5–10mm vs <5mm 3.79 1.02 14.07 0.0468 <0.0001
11–15mm vs <5mm 16.44 4.80 56.27 <0.0001
16–20mm vs <5mm 21.64 5.97 78.40 <0.0002
>20mm vs <5mm 41.31 12.35 138.14 <0.0003
Lens status pre-OGI Pseudophakic vs phakic 1.87 1.15 3.04 0.0117 0.0386
Aphakic vs phakic 0.77 0.09 6.46 0.8080
Lens disruption including implant disruption Yes vs no 0.91 0.60 1.38 0.6718
Uveal prolapse Yes vs no 6.10 3.11 11.99 <0.0001
Vitreous hemorrhage at time of wound closure Yes vs no 1.36 0.89 2.07 0.1548
Intraocular inflammation with or without hypopyon at time of presentation Yes vs no 0.30 0.12 0.77 0.0123
Retinal detachment Yes vs no 1.76 1.13 2.75 0.0126
Endophthalmitis Yes vs no 1.28 0.50 3.29 0.6034
Time to surgery from injury >24h vs <24h 0.77 0.44 1.35 0.3598
Vitrectomy at time of globe repair Weck-Cel vs no 1.04 0.61 1.79 0.8824 0.8413
Anterior vitrectomy vs no <0.001 <0.001 >999.999 0.9837
Posterior vitrectomy vs no 0.57 0.17 1.96 0.3754
Lensectomy Yes vs no 1.03 0.50 2.12 0.9434
Age (Years) Continuous 1.01 1.00 1.02 0.0144
Presenting VA LogMAR Continuous 13.35 6.59 27.07 <0.0001
Presenting VA <20/400 vs ≥20/400 16.48 3.99 68.13 0.0001

Notes: Bolded rows within the table denote statistically significant risk factors and their associated odds ratios and p-values.

Abbreviations: RAPD, relative afferent pupillary defect; IOFB, intraocular foreign body.