Table 2.

Flavonoids present in the extract and their affinity to binding to the ERs α and β.

Ligand	ER α (Kcal/mol)	ER β (Kcal/mol)
Estradiol	−7.7 to −6.7	−7.5 to −6.4
Finasteride	−7 to −6.8	−8.2 to −6.6
Formononetin	−7.2 to−6.4	−8 to −6.2
Kaempferol-3-O-glucoside	−7.9 to −6.9	−8.5 to −7.1
Kaempferol-3-O-sophoroside	−7.4 to −6.7	−8.0 to −7.4
Kaempferol-3-O-neohesperidoside	−7.9 to −7.3	−7.3 to −6.8
Quercetin-3-O-neohesperidoside	−7.8 to −6.8	−7.9 to−7.3
Calycosin-7-O-beta-D-glucoside	−7.6 to −7	−7.7 to −7.2

Molecular docking results indicated that all ligands had a high affinity (<−6.3) to receptors.