FIG 1.

Concordance between p53 expressions by IHC with mutation in TP53. (A) Examples of WT p53 staining (both low and high patterns), null p53, and overexpression of p53. Also shown are cases with equivocal staining for p53 and focal regions of p53 overexpression. (B) Overall distribution of p53 expression by IHC in cases with available data. (C) Percent of cases with WT p53 staining, null staining, or OE by histology. (D) Concordance on the basis of the absence (WT) or presence of a TP53 mutation with p53 expression by IHC. (E) Concordance on the basis of the specific type of TP53 mutation. IHC, immunohistochemistry; OE, overexpressed; WT, wild-type.