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. 2022 Jun 3;40(28):3289–3300. doi: 10.1200/JCO.21.02506

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FIG 4. — Integrated analysis of p53 using IHC and sequencing data improves the prediction of response to bevacizumab plus chemotherapy. (A) Decision tree for integrated analysis of p53 by IHC and sequencing. Kaplan-Meier curves for (B) PFS and (C) OS for the integrated categories independent of treatment. Kaplan-Meier curves for (D) PFS and (E) OS for the integrated category of p53^OE/TP53^mut by treatment arm. IHC, immunohistochemistry; OE, overexpressed; OS, overall survival; PFS, progression-free survival.