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. 2021 Sep 3;36(10):933–939. doi: 10.1038/s41371-021-00598-1

Table 2.

Hazard ratios of cardiovascular events by systolic blood pressure categories within the normal range.

Parameter SBP, mmHg
90–99 100–109 110–119 120–129
Case/n 24/1548 106/4599 265/8136 452/11246
Incidence/1000 person-years 1.45 2.15 3.06 3.80
Model 1 Ref. 1.48 (0.95–2.30) 2.10 (1.38–3.18)a 2.60 (1.72–3.92)a
Model 2 Ref. 1.20 (0.77–1.88) 1.43 (0.94–2.18) 1.45 (0.96–2.19)
Model 3 Ref. 1.12 (0.69–1.80) 1.21 (0.75–1.93) 1.09 (0.67–1.77)
Model 4 Ref. 1.16 (0.71–1.89) 1.25 (0.78–2.02) 1.13 (0.69–1.86)

Model 1: unadjusted. Model 2: adjusted for age and sex (male/female). Model 3: adjusted for age, sex (male/female), alcohol consumption status (never and past, current, ≥1 time/day), ever smoking (yes/no), education level (elementary school, high school or above), exercise (none, occasionally or frequently, ≥1 times/week), prediabetes (yes/no), family history of cardiovascular diseases (yes/no), diastolic blood pressure, body mass index, serum concentrations of total cholesterol, high-density lipoprotein cholesterol, glucose, uric acid and C-reactive protein, and estimated glomerular filtration rate. Model 4 was a competing risk model of death which adjusted for all the confounders in model 3. Compared with reference group.

aP  <  0.01.