Table 5.

Complications post-procedures during follow-up period.

Study Author (Year)	Turagam-HFIB 2 (2021) [22]		Turagam-HFIB 1 (2021) [22]a		Steinberg et al., (2020) [21]		Kiuchi et al., (2018) [20]		Kiuchi et al., (2017) [19]		Kiuchi et al., (2016) [18]		Pokushalov et al., (2014) [17]
Study groups	PVI + RDN	PVI	PVI + RDN	PVI	PVI + RDN	PVI	PVI + RDN	PVI + Spironolactone	PVI + RDN	PVI	PVI + RDN	PVI	PVI + RDN	PVI
Femoral venous vascular events	2/28	0/22	0	1/17	6/154	4/148	0	0	0	0	0	NR	0	0
Transient phrenic nerve plasty	0	0	0	0	1/154	1/148	0	0	0	0	0	NR	0	0
Cardiac tamponade	0	0	0	0	0/154	1/148	0	0	0	4/?b	0	NR	1/41	0
Pneumothorax	0	0	0	0	0/154	1/148	0	0	0	0	0	NR	0	0
Hospitalization	0	0	0	0	8/154	18/148	0	0	0	0	0	NR	0	0
Death	0	0	0	0	2/154	2/148	0	0	0	0	0	NR	0	0
Stroke	0	0	0	1/17	0	0	0	0	0	0	0	NR	0	0
Renal artery stenosis	0	0	3/13	0	0	0	0	0	0	0	0	NR	0	0
Renal artery dissection in procedure	0	0	3/13	0	0	0	0	0	0	0	0	NR	0	0
Total	2/28	0/22	6/13	2/17	17/154	27/148	0	0	0	-	0	NR	1/41	0

Data reported as number of events over sample size.

PVI pulmonary vein isolation, RDN renal denervation, NR not reported.

^aThis study was terminated early due to a high rate of renovascular complications.

^bFour cardiac tamponade events were reported in this study, but it was not clear which PVI group this occurred in.