Table 2.
Comparison of biochemical variables between COVID-19 and normal pregnant groups in normal and cesarean delivery.
| Variables | Normal delivery groups | p value | Cesarean delivery groups | p value∗ | ||
|---|---|---|---|---|---|---|
| COVID-19 (n=57) | Normal (n=46) | COVID-19 (n=8) | Normal (n=20) | |||
| Mean ± SD/median (IQR) | Mean ± SD/median (IQR) | Median (IQR) | Median (IQR) | |||
| Gestational week | 38.8 ± 1.8 | 39.2 ± 0.9 | 0.185 | 39 (1) | 38.5 (1) | 0.117 |
| Age, year | 26.8 ± 4.8 | 27.2 ± 4.6 | 0.634 | 25.5 (8) | 26 (6) | 0.838 |
| Parity, n | 2.9 ± 1.6 | 3.1 ± 1.5 | 0.506 | 2 (3) | 2 (2) | 0.812 |
| WBC, K/uL | 16.4 ± 5.6 | 13.8 ± 4.5 | 0.012 | 15.5 (9) | 12 (5) | 0.185 |
| Lymphocyte, K/uL | 10.3 ± 6.2 | 14.0 ± 7.8 | 0.010 | 13.5 (9) | 11 (7) | 0.160 |
| Neutrophil, K/uL | 82.6 ± 6.7 | 78.4 ± 8.8 | 0.008 | 80 (6) | 84 (10) | 0.169 |
| Neutrophil/lymphocyte ratio | 0.13 ± 0.1 | 0.19 ± 0.14 | 0.013 | 0.17 (0.12) | 0.13 (0.10) | 0.186 |
| Hemoglobin, g/dL | 11.3 ± 1.4 | 11.3 ± 1.4 | 0.895 | 12 (3) | 11 (1) | 0.711 |
| Htc, % | 35.5 ± 4.1 | 35.2 ± 3.6 | 0.722 | 35.5 (9) | 35 (4) | 0.939 |
| Platelet, K/uL | 234.3 ± 61.2 | 241.2 ± 66.0 | 0.589 | 227.5 (117) | 214.5 (86) | 0.509 |
| Glucose, mg/dL | 91.5 ± 26.9 | 95.9 ± 25.8 | 0.401 | 88 (34) | 86 (22) | 0.610 |
| Urea, mg/dL | 18.3 ± 5.0 | 17.9 ± 5.2 | 0.686 | 18.5 (7) | 16 (4) | 0.071 |
| Creatinine, mg/dL | 0.6 ± 0.1 | 0.59 ± 0.1 | 0.660 | 0.6 (0.1) | 0.6 (0.1) | 0.226 |
| AST, U/L | 28.4 ± 9.7 | 25.3 ± 6.9 | 0.071 | 26 (16) | 24 (6) | 0.557 |
| ALT∗, U/L | 15 (7) | 12.5 (7) | 0.037 | 13.5 (9) | 15 (6) | 0.523 |
| D-dimer, ug/L | 1051.3 ± 675.2 | −(n=0) | NA | −(n=2) | −(n=1) | NA |
| CRP∗, mg/dL | 8 (11) | 4 (4) | 0.008 | 13 (22) | 6 (5.5) | 0.052 |
| Ferritin∗, ng/mL | 22 (34) (n=23) | 11 (44) (n=11) | 0.699 | 14 () | 10.5 (13.5) | 0.410 |
| Duration of hospital stay, day | 2.5 ± 0.9 | 2.2 ± 0.8 | 0.152 | 3 (1) | 3 (0) | 0.252 |
| Week of birth | 38.8 ± .1.8 | 39.2 ± 0.9 | 0.140 | 40 (1) | 38.5 (1) | 0.004 |
| Fetal weight, gr | 3187.5 ± 531.8 | 3237.2 ± 377.0 | 0.623 | 3130 (1176) | 3220 (479) | 0.958 |
| Apgar1. min | 7.7 ± 1.2 | 8.0 ± 0.5 | 0.235 | 8 (1) | 7.5 (1) | 0.013 |
| Apgar 5.min | 8.9 ± 1.3 | 9.1 ± 0.5 | 0.232 | 9 (1) | 9 (0) | 0.059 |
AST, aspartate aminotransferase; ALT, alanine aminotransferase; CRP, C-reactive protein, white blood cell (WBC); N/L, neutrophil/lymphocyte ratio, NA, not applicable. Independent t test and ∗Mann–Whitney U test were used and p < 0.05 was considered significant.