Table 1.

Characteristics of included studies.

Author and year	Study period	Age group	Study design	Sample size	Sealant		Fluoride varnish		Sealant		Fluoride varnish
					Caries	Total	Caries	Total	Mean (SD)	Total	Mean (SD)	Total
Bravo et al., 1996 [14]	24 month	6-8	RCT	362‬‬‬‬‬‬‬‬‬‬‬‬‬	25	238	71	252	—	—	—	—
Bravo et al., 1997 [15]	24 month	6-8	RCT	362	—	—	—	—	0.96 (1.24)	—	1.33 (1.82)	—
Liu et al., 2012 [16]	24 months	9.1	Randomized parallel	501	11	367	16	358	—	—	—	—
Salem et al., 2014 [17]	24 months	6-7	Randomized parallel	400	140	691	150	716	0.41 (0.92)	691	0.33 (0.77)	716