Table 3.
Effect of the medication on pain relief.
| Percentage of patient replies indicating pain reduction by x points on the NRS with a given drug (retrospective evaluation). | N | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | 5 | 6 | 8 | Pain reduction in NRS (median, range) | ||
| NSAID | 6.2 | 18.5 | 38.5 | 16.9 | 16.9 | 3.1 | 0.0 | 0.0 | 2.3 (2, 0–5) | 64 |
| Metamizole | 12.1 | 15.2 | 51.5 | 15.2 | 0.0 | 3.0 | 0.0 | 3.0 | 2.0 (2, 0–8) | 33 |
| Amitriptyline | 45.0 | 15.0 | 15.0 | 20.0 | 5.0 | 0.0 | 0.0 | 0.0 | 1.3 (1, 0–4) | 20 |
| SNRI | 38.9 | 33.3 | 16.7 | 11.1 | 0.0 | 0.0 | 0.0 | 0.0 | 1.0 (1, 0–3) | 18 |
| Drugs taken by < 15 patients | ||||||||||
| Weak opioid | 0.0 | 22.2 | 44.4 | 0.0 | 22.4 | 11.0 | 0.0 | 0.0 | 2.6 (2, 1–5) | 9 |
| Pregabalin | 12.5 | 0.0 | 50.0 | 37.5 | 0.0 | 0.0 | 0.0 | 0.0 | 2.1 (2, 0–3) | 8 |
| Strong opioid | 0.0 | 14.3 | 0.0 | 71.4 | 0.0 | 14.3 | 0.0 | 0.0 | 3.0 (3, 1–5) | 7 |
| COX-2 inhibitor | 0.0 | 14.3 | 28.6 | 42.9 | 14.3 | 0.0 | 0.0 | 0.0 | 2.6 (3, 1–4) | 7 |
| Muscle relaxant | 33.3 | 16.7 | 33.3 | 0.0 | 16.7 | 0.0 | 0.0 | 0.0 | 1.5 (2, 0–4) | 6 |
| Acetaminophen | 16.7 | 16.7 | 33.3 | 16.7 | 16.7 | 0.0 | 0.0 | 0.0 | 2.0 (2, 0–4) | 6 |
| Cannabinoid | 0.0 | 0.0 | 25.0 | 25.0 | 25.0 | 0.0 | 25.0 | 0.0 | 3.7 (4, 2–6) | 4 |
| Guaifenesin | 33.3 | 0.0 | 0.0 | 0.0 | 33.3 | 0.0 | 33.3 | 0.0 | 3.3 (4, 0–6) | 3 |
| Flupirtine | 0.0 | 33.3 | 33.3 | 0.0 | 33.3 | 0.0 | 0.0 | 0.0 | 2.3 (2, 1–4) | 3 |
| SSRI | 0.0 | 50.0 | 0.0 | 50.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.0 (2, 1–3) | 2 |
| Triptans1 | 0.0 | 0.0 | 0.0 | 50.0 | 50.0 | 0.0 | 0.0 | 0.0 | 3.5 (3.5, 3-4) | 2 |
| Corticosteroid | 0.0 | 0.0 | 0.0 | 0.0 | 100.0 | 0.0 | 0.0 | 0.0 | 4.0 (4) | 1 |
| Lidocaine | 0.0 | 0.0 | 0.0 | 0.0 | 100.0 | 0.0 | 0.0 | 0.0 | 4.0 (4) | 1 |
| All | 2.1 (2, 0–8) | 195 | ||||||||
N, the number of patients' replies when asked about a given drug. 1Used in migraine attacks.