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. 2022 Sep 22;2022:1217717. doi: 10.1155/2022/1217717

Table 4.

Effect of the medication categories (current treatment) on pain relief in NRS-points, in the subgroups with and without reduction of skin innervation.

Reduced IENFD Normal IENFD P All
N Response (median, range) N Response (median, range) N Response (median, range)
NSAID 16 2, 0–5 21 2, 0–4 0.33 65 2, 0–5
Metamizole 9 2, 0–3 5 2, 1–3 0.36 33 2, 0–8
Amitriptyline 5 0, 0–2 6 1, 0–4 0.24 20 1, 0–4
SNRI 8 1, 0–2 3 0, 0 0.13 18 1, 0–3

N, the number of patients replies when asked about a given drug; IENFD, normal and reduced intraepidermal nerve density.