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. 2022 Mar 11;30(10):1191–1194. doi: 10.1038/s41431-022-01076-z

Fig. 2. Part of networks depicting gene interactions among LHX4, NR5A1, and FOXL2 in pituitary and ovary during development. Pituitary: NR5A1 co-regulates with PITX1 and POU1F1 the transcription of LHX3.

Fig. 2

FOXL2 transcription needs LHX3 and is enhanced by LHX4 Ovary: SF-1 transactivates ovarian AMH in a FOXL2-dependent manner and FOXL2 is required for the binding of SF-1 to the AMH promoter.