Table 2.

Study cohort of HLA-A*02 positive patients with chronic HBV infection

Characteristics	HLA-A*02 positive patients (n=35)*
	HBsAg groups (IU/mL)		HBcrAg groups (Log U/mL)
	<100	≥10 000	<3	≥3
Number of patients	19	16	25	10
HBsAg (IU/mL): median (range)	29 (0.76–116)†	18 303 (10 266–52 891)	43 (0.76–27 064)	19 870.5 (10 266–52 891)
HBcrAg (LogU/mL): median (range)	2 (2–2.5)	3.05 (2–4.3)	2 (2–2.8)	3.2 (3–4.3)
Sex (male/female)	11/8	7/9	15/10	3/7
Age (years): median (range)	51 (29–67)	35 (19–57)	50 (29–67)	28 (19–41)
ALT level (IU/L): median (range)	19 (4–46)	24 (13–126)	20 (4–50)	25 (13–126)
HBV DNA <2000 IU/mL (%)	94.7	100	96	100
HBeAg (-/+/n.d.)	15/0/4	12/0/4	20/0/5	7/0/3
NA therapy / no treatment / n.d.	13/4/2	4/12/0	15/8/2	2/8/0

*One patient (HBsAg=0.76 IU/mL and HBcrAg=2 Log U/mL) is excluded from final phenotyping analysis because the frequencies of antigen-specific cells were below the limit of detection (10 dextramer positive cells).

†HBsAg level of one patient from the group of HBsAg <100 is 116 IU/mL.

ALT, alanine transaminase; HBcrAg, hepatitis B core-related antigen; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; NA, nucleos(t)ide analogue; n.d., not determined.