TABLE 3.

Classification performance across methods.

Method	Laterality	Threshold	Sensitivity	Specificity	PPV	NPV	Accuracy
Optimal thresholds	Affected	≥20	85.51	77.60	55.58	94.23	79.55
	Non-affected	≥38	83.87	76.29	75.34	84.56	79.80
	Bilateral	≥20/≥38	76.08	82.33	50.66	93.52	81.13
Logistic regression	Affected	≥0.5*	78.56	79.89	56.15	91.91	79.56
	Non-affected	≥0.5*	79.46	75.05	72.26	81.71	77.04
	Bilateral	≥0.5/≥0.5*	79.13	79.41	47.81	94.10	79.35
Conventional threshold	Affected	>2	94.42	63.68	46.01	97.21	71.27
	Non-affected	>2	95.03	57.56	65.92	93.06	74.93
	Bilateral	>0	92.08	66.08	39.29	97.22	71.08

Legend: optimal thresholds on group level; ^∗defold value of probability for logistic regression.