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Old Ghrl−/− mice showed increased gut permeability and inflammation. (A) Plasma level of fluorescence emitted from FITC-dextran translocated from gut. (B and D) Colon samples from 22M to 28M mice were processed and used for cytokine measurements: (B) IL-1β, (C) IL-6, and (D) TNF-α.
*P < 0.05, WT versus Ghrl−/− mice.
