Figure 4.
Dendritic cell miRNAs regulate pro- and anti-tumor immune responses in the TME. Dendritic cells are a central hub for priming pro- and anti-tumor immune responses in cancer. Many DC miRNAs change TAA presentation to and co-stimulation of T cells, required for T-cell–mediated anti-tumor immunity. Several other miRNAs suppress the proinflammatory functions and promote the immune suppressive function of DCs.