Table 1.

Shanghai Score System for diagnosing BrS^a

Factor	Points
ECG (12-lead/ambulatory)b
Spontaneous type 1 Brugada pattern on standard or Brugada ECG	3.5
Fever-induced type 1 Brugada pattern on standard or Brugada ECG	3
Type 2 or 3 Brugada ECG pattern that converts with sodium channel-blocking drug challenge	2
Clinical historya
Unexplained cardiac arrest or documented ventricular fibrillation/polymorphic ventricular tachycardia	3
Nocturnal agonal respirations	2
Suspected arrhythmic syncope	2
Syncope of unclear mechanism or unclear aetiology	1
Atrial flutter or fibrillation in patients < 30 years without alternative aetiology	0.5
Family historya
First- or second-degree relative with definite BrS	2
Suspicious SCD (during fever, at night, or when taking Brugada-aggravating drugs) in a first- or second-degree relative	1
Unexplained SCD < 45 years in a first- or second-degree relative with negative autopsy	0.5
Genetic test result
Probable pathogenic mutation in BrS susceptibility gene	0.5
Total score (requires ≥ 1 ECG finding)
≥ 3.5 points	Probable or definite BrS
2–3 points	Possible BrS
< 2 points	Non-diagnostic

BrS Brugada syndrome, ECG electrocardiogram, SCD sudden cardiac death

^a This table was adapted from an original table as reported by Antzelevitch et al. [4]

^b Only award points once for highest score within each category