Table 1.

Recommendations for monocyte evaluation in the blood or bone marrow smears by Goasguen et al. (28).

	Nuclear shape	Chromatin	Cytoplasm	Comments
Monoblast	Round/oval	Delicate/lace-like Nucleolus prominent	Basophilic Rare azurophilic Granules	Large: 20–30 μm
Promonocyte	Convoluted/indented	Delicate/lace-like Nucleolus prominent	Variably basophilic Variable azurophilic Granules	Except for nuclear shape, very similar to monoblast
Immature monocyte	Convoluted/indented	More condensed Rare nucleolus	Less basophilic than promonocyte or blast, but more basophilic than mature monocyte	Resemble monocytes but less mature and smaller
Monocyte	Lobulated/indented	Condensed No visible nucleolus	Gray Occasional azurophilic granules Occasional vacuoles	Large: 20–25 μm