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. 2022 Sep 28;13:995972. doi: 10.3389/fendo.2022.995972

Table 1.

Correlation between GPI expression and the clinicopathological features of the BRCA cases.

Characteristic Low expression of GPI High expression of GPI p
n 541 542
T stage, n (%) 0.004
 T1 156 (14.4%) 121 (11.2%)
 T2 293 (27.1%) 336 (31.1%)
 T3 79 (7.3%) 60 (5.6%)
 T4 12 (1.1%) 23 (2.1%)
N stage, n (%) 0.154
 N0 246 (23.1%) 268 (25.2%)
 N1 185 (17.4%) 173 (16.3%)
 N2 54 (5.1%) 62 (5.8%)
 N3 46 (4.3%) 30 (2.8%)
M stage, n (%) 0.340
 M0 436 (47.3%) 466 (50.5%)
 M1 7 (0.8%) 13 (1.4%)
Pathologic stage, n (%) 0.199
 Stage I 97 (9.2%) 84 (7.9%)
 Stage II 296 (27.9%) 323 (30.5%)
 Stage III 131 (12.4%) 111 (10.5%)
 Stage IV 7 (0.7%) 11 (1%)
Race, n (%) 0.049
 Asian 22 (2.2%) 38 (3.8%)
 Black or African American 85 (8.6%) 96 (9.7%)
 White 391 (39.3%) 362 (36.4%)
Age, n (%) 0.016
 ≤60 280 (25.9%) 321 (29.6%)
 >60 261 (24.1%) 221 (20.4%)
Histological type, n (%) <0.001
 Infiltrating ductal carcinoma 340 (34.8%) 432 (44.2%)
 Infiltrating lobular carcinoma 152 (15.6%) 53 (5.4%)
PR status, n (%) <0.001
 Negative 127 (12.3%) 215 (20.8%)
 Indeterminate 1 (0.1%) 3 (0.3%)
 Positive 387 (37.4%) 301 (29.1%)
ER status, n (%) <0.001
 Negative 77 (7.4%) 163 (15.7%)
 Indeterminate 0 (0%) 2 (0.2%)
 Positive 438 (42.3%) 355 (34.3%)
HER2 status, n (%) 0.482
 Negative 264 (36.3%) 294 (40.4%)
 Indeterminate 7 (1%) 5 (0.7%)
 Positive 68 (9.4%) 89 (12.2%)
PAM50, n (%) <0.001
 Normal 33 (3%) 7 (0.6%)
 LumA 354 (32.7%) 208 (19.2%)
 LumB 83 (7.7%) 121 (11.2%)
 HER2 21 (1.9%) 61 (5.6%) 
 Basal 50 (4.6%) 145 (13.4%)
Menopause status, n (%) 0.445
 Pre 108 (11.1%) 121 (12.4%)
 Peri 22 (2.3%) 18 (1.9%)
 Post 362 (37.2%) 341 (35.1%)
Anatomic neoplasm subdivisions, n (%) 0.153
 Left 269 (24.8%) 294 (27.1%)
 Right 272 (25.1%) 248 (22.9%)
Radiation therapy, n (%) 0.092
 No 208 (21.1%) 226 (22.9%)
 Yes 296 (30%) 257 (26%)
 Age, median (IQR) 60 (50, 67) 56 (47, 67) 0.027

PR, progesterone receptor; ER, estrogen receptor; IQR, interquartile range.