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. 2022 Sep 28;13:987800. doi: 10.3389/fphar.2022.987800

TABLE 2.

Effect of MPTA on sperm malformation in mice (n = 5).

Groups Sperm test count Abnormal sperm count Sperm abnormality rate Percentage of each type of abnormal sperm (%)
No hook Banana-shaped Amorphous Fathead Tail-folded Double-headed Double-tailed
241.00 mg/kg 5 × 1000 134 2.76 ± 0.84 12.69 ± 0.82 14.93 ± 0.15** 33.58 ± 0.47 14.18 ± 0.27* 14.93 ± 0.73 3.73 ± 0.65 5.97 ± 0.14**
120.50 mg/kg 5 × 1000 141 2.91 ± 0.82 14.89 ± 0.94* 14.18 ± 0.59** 34.04 ± 0.88 13.48 ± 0.69 12.77 ± 0.79 2.84 ± 0.41 7.80 ± 0.51*
60.25 mg/kg 5 × 1000 118 2.42 ± 0.63 10.17 ± 0.50 11.86 ± 0.66** 36.44 ± 1.23 13.56 ± 0.52 11.02 ± 0.67 5.93 ± 0.49* 11.02 ± 0.75
Negative control 5 × 1000 135 2.78 ± 0.91 11.85 ± 0.70 21.48 ± 1.19 29.63 ± 1.12 10.37 ± 0.73 13.33 ± 0.79 2.96 ± 0.41 10.37 ± 0.73
Positive control 5 × 1000 418 9.12 ± 1.44** 9.57 ± 0.97 7.66 ± 1.05** 51.20 ± 2.13** 11.00 ± 1.49 10.77 ± 1.41 3.83 ± 0.70 5.98 ± 1.07**

Note: Data are compared with negative controls, * indicates significant differences (p < 0.05), ** indicates significant differences (p < 0.01).