TABLE 2.
Effect of MPTA on sperm malformation in mice (n = 5).
| Groups | Sperm test count | Abnormal sperm count | Sperm abnormality rate | Percentage of each type of abnormal sperm (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No hook | Banana-shaped | Amorphous | Fathead | Tail-folded | Double-headed | Double-tailed | ||||
| 241.00 mg/kg | 5 × 1000 | 134 | 2.76 ± 0.84 | 12.69 ± 0.82 | 14.93 ± 0.15** | 33.58 ± 0.47 | 14.18 ± 0.27* | 14.93 ± 0.73 | 3.73 ± 0.65 | 5.97 ± 0.14** |
| 120.50 mg/kg | 5 × 1000 | 141 | 2.91 ± 0.82 | 14.89 ± 0.94* | 14.18 ± 0.59** | 34.04 ± 0.88 | 13.48 ± 0.69 | 12.77 ± 0.79 | 2.84 ± 0.41 | 7.80 ± 0.51* |
| 60.25 mg/kg | 5 × 1000 | 118 | 2.42 ± 0.63 | 10.17 ± 0.50 | 11.86 ± 0.66** | 36.44 ± 1.23 | 13.56 ± 0.52 | 11.02 ± 0.67 | 5.93 ± 0.49* | 11.02 ± 0.75 |
| Negative control | 5 × 1000 | 135 | 2.78 ± 0.91 | 11.85 ± 0.70 | 21.48 ± 1.19 | 29.63 ± 1.12 | 10.37 ± 0.73 | 13.33 ± 0.79 | 2.96 ± 0.41 | 10.37 ± 0.73 |
| Positive control | 5 × 1000 | 418 | 9.12 ± 1.44** | 9.57 ± 0.97 | 7.66 ± 1.05** | 51.20 ± 2.13** | 11.00 ± 1.49 | 10.77 ± 1.41 | 3.83 ± 0.70 | 5.98 ± 1.07** |
Note: Data are compared with negative controls, * indicates significant differences (p < 0.05), ** indicates significant differences (p < 0.01).