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(A) Representative plot for Fluorescence-activated cell sorting (FACS) gating for AIM+ (OX40+ CD137+) cells gated on CD4+ T cell; (B) AIM+ CD4+ T cell reactivity in unexposed control (n=10) and COVID-19 cases (n=15) between the negative control (DMSO) and different antigen-specific stimulations (Spike, Non-spike MP, CMV, PHA). Wilcoxon matched pairs signed rank test was performed to compare between groups. *p <0.05; **p <0.01; ***p < 0.001; ****p < 0.0001; ns: non-significant.
