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. 2022 Sep 28;13:929849. doi: 10.3389/fimmu.2022.929849

Figure 5.

Figure 5

AIM expression in different categories of COVID-19 patients (asymptomatic (n=5), mild (n=5), moderate (n=6), and Severe (n=6)) immediately after infection (Day1) and after one month of infection (Day 28) and compared with both unexposed (n=10) and healthy (n=9) controls. (A) Stimulation of AIM+ (OX40+ CD40L+ and OX40+ CD137+) CD4+ T cells in response to Spike antigen; (B) Stimulation of AIM+ (OX40+ CD40L+ and OX40+ CD137+) CD4+ T cells in response to non-spike megapool peptides; (C) Stimulation of AIM+ (CD137+ CD69+) CD8+ T cells in response to CD8-A and CD8-B megapool peptides. Paired t test is done to compare statistically groups. *p<0.05; **p<0.01; ns: non-significant.