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. 2022 Sep;11(9):1877–1895. doi: 10.21037/tlcr-22-230

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2022 Translational Lung Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Analysis of CNV and mutations on USO1 expression in LUAD and LUSC. The effects of CNV on USO1 expression were analysed using cBioPortal for (A) LUAD and (B) LUSC. A screen for mutated genes which are correlated with altered USO1 expression was conducted using muTarget and validated using TIMER2. Significant mutated genes identified were (C) KRT47, (D) INSR and (E) OR10X1. CNV, copy number variations; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma.