Table 5. Correlations between USO1 mRNA levels and expression of key genes in NSCLC.
Gene | LUAD | LUSC | ||||
---|---|---|---|---|---|---|
Partial cor. | P value | Partial cor. | P value | |||
USO1 | TP53 | 0.0347 | 2.9×10−1 | 0.0370 | 0.673439 | |
KRAS | 0.428 | 4.25×10−23 | 0.213 | 4.42×10−6 | ||
EGFR | 0.368 | 8.46×10−17 | 0.260 | 1.44×10−8 | ||
ERBB2 | 0.199 | 4.48×10−5 | 0.101 | 0.05 | ||
PIK3CA | 0.520 | 4.46×10−35 | 0.353 | 2.56×10−15 | ||
ALK | 0.073 | 0.205 | 0.087 | 0.14623117 |
Analysis was conducted using TIMER 2.0. Results are presented as purity-corrected partial Spearman’s rho value and statistical significance. Correlation cut-off values of the Spearman coefficient was set to R>0.33 (positive correlation) and R<-0.33 (negative correlation). Neg: negative correlation (P<0.05, P<0); Pos: Positive correlation (P<0.05, P>0); ns, not significant (P>0.05). NSCLC, non-small cell lung cancer; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma.