Table 5. Multivariate analysis for PFS.
| Variables | HR (95% CI) | P value |
|---|---|---|
| Age ≥75 years | 1.15 (0.78–1.68) | 0.490 |
| Female | 1.01 (0.75–1.35) | 0.960 |
| Poor ECOG PS at first-line initiation | 1.04 (0.71–1.53) | 0.840 |
| Poor ECOG PS at AMR initiation | 1.79 (1.26–2.54) | 0.001 |
| Use of platinum plus etoposide at the first-line treatment | 1.41 (1.00–1.98) | 0.048 |
PFS, progression-free survival; HR, hazard ratio; CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; AMR, amrubicin.