Figure 1.

Histological grade of tumor response in patients treated by neoadjuvant chemotherapy. Pathological appearances of histological grades are shown (HE staining). (A) Grade 0 (no effect): No evidence of treatment effect. (B) Grade 1 (slight effect): Viable tumor cells occupy >1/3 of the tumor area. (C) Grade 2 (considerable effect): Viable tumor cells remain in <1/3 of the tumor area. (D) Grade 3 (complete response): No viable tumor cells remain. HE staining (magnification, ×20). Scale bar: 50 µm. HE, hematoxylin and eosin.