Table I.
Clinicopathological characteristics of patients who underwent upfront surgery vs. NAC followed by surgery.
| Factors | Upfront surgery (n=146) | NAC (n=14) | P-value |
|---|---|---|---|
| Age | 0.19 | ||
| ≥70 years | 79 | 5 | |
| <70 years | 67 | 9 | |
| Sex | 0.75 | ||
| Male | 109 | 11 | |
| Female | 37 | 3 | |
| Tumor location | 0.96 | ||
| Upper/Middle | 84 | 8 | |
| Lower | 62 | 6 | |
| Tumor size | 0.62 | ||
| ≥50 mm | 83 | 7 | |
| <50 mm | 63 | 7 | |
| Differentiation | 0.08 | ||
| Well/Moderate | 74 | 3 | |
| Poor | 58 | 7 | |
| Others | 14 | 4 | |
| cT stage | 0.75 | ||
| T1-3 | 76 | 6 | |
| T4 | 70 | 8 | |
| cN stage | 0.73 | ||
| N0-1 | 80 | 7 | |
| N2-3 | 66 | 7 | |
| Surgical procedure | 0.62 | ||
| DG | 62 | 5 | |
| TG | 84 | 9 | |
| NAC regimen | - | ||
| DCS | - | 9 | |
| SOX | - | 5 | |
| Histological grade | - | ||
| 0, 1 | - | 6 | |
| 2, 3 | - | 8 |
DCS, docetaxel + cisplatin + S-1; DG, distal gastrectomy; NAC, neoadjuvant chemotherapy; SOX, S-1 + oxaliplatin; TG, total gastrectomy.